International Journal of Multidisciplinary Education and Research

International Journal of Multidisciplinary Education and Research


International Journal of Multidisciplinary Education and Research
Vol. 5, Issue 3 (2020)

The role of pepaya fruit extract (Carica papaya. L) As a complementer therapy on the change of hemoglobin content in the white rat (Rattus norvegicus) anemia


Wenty Ika Ariani, Runjati, Ari Suwondo

Background: Anemia is a common health problem that occurs throughout the world, where 50% of cases of anemia are caused by iron deficiency. One alternative for preventing anemia is to use papaya fruit extracts that contain antioxidants good for the body and blood profile levels but are underutilized.
Objective: To determine the effectiveness of papaya fruit extracts as an alternative to increasing hemoglobin levels in anemic white rats.
Methods: This type of research method used is True Experimentation. The research design used was a pretest and post-test control group design. With a sample size of 16 divided into 2 groups, namely the intervention group given papaya fruit extract and the control group given aquadest. Data analysis using Friedman and Post hoc Wilcoxon.
Results: Increased hemoglobin level after papaya fruit extract in the treatment group was 1,120 g / dl (p <0.05).
Conclusion: Papaya fruit extract significantly influences hemoglobin level.
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